We are pleased to announce that the next International Symposium on Nonparametric Statistics will be held in Paphos, Cyprus, from June 14 – 18, 2021. In the tradition of the successful ISNPS conferences in Chalkidiki (2012), Cadiz (2014), Avignon (2016) and Salerno (2018), this meeting will bring together new and established researchers to consider a broad range of topics from nonparametric and semiparametric statistics. The program will include plenary lectures, invited and contributed talks, and posters.