The aim of INDSTATS2019 is to engage leading experts and junior members in all topics related to statistics and data sciences. The four and half days of vibrant conference activities will consist of pre-conference short courses (on Dec 26th), plenary talks by eminent speakers, invited sessions, contributed sessions, panel discussions and student paper competitions. Our past annual conferences in India and the US have attracted over 300 participants, across academics, industry, government, regulatory agencies and non-profit organizations. Specific topics include Probability and Statistics, Survival Analysis, Personalized medicine, Big Data and Machine Learning Methodology, Econometrics, Bayesian Statistics, Clinical trial Data and Innovations, High-dimensional data analysis, etc.