This multidisicplinary conference focuses on the following topics: Monte Carlo, quasi-Monte Carlo, Markov chain Monte Carlo; Digital nets and lattice rules; Discrepancy theory; Complexity and tractability of multivariate problems; Multi-level Monte Carlo; Sequential Monte Carlo and particle methods; Rare event simulation; Randomized quasi-Monte Carlo; Variance reduction methods; MC/QMC methods in physics, chemistry, finance, computer graphics and other areas.