To keep up in today’s competitive marketplace, enterprise business entities must be able to constantly transform and improve their business. In order to improve, enterprise business entities have started to integrate sophisticated business analytics and big data, internal and external, in their internal operational processes for sales, marketing, finance, management, procurement, etc. Statistical methodology can play a powerful role in developing such an effective business transformation. In this conference, we explore how businesses increase efficiency, support decision-making under uncertainty, improve business operations and ultimately transform their business by using statistics.