The goal of this workshop is to foster the communication of communities broadly working in the area of data science, with a particular focus of stimulating increased interactions between statisticians, computer scientists, and domain experts in order to ambitiously attack important scientific problems involving big and complex data. As a first step, this workshop will provide an intimate setting for approximately 50 researchers (with substantial diversity). The emphasis will be on defining data science challenges in a variety of areas, providing a variety of perspectives and exposure to new problems, while jump-starting a dialog on solving these problems and enhancing communication across communities.